BENZYL 3-(CHLOROCARBONYL)PIPERIDINE-1-CARBOXYLATE

BENZYL 3-(CHLOROCARBONYL)PIPERIDINE-1-CARBOXYLATE - Names and Identifiers

Name	Benzyl 4-(chlorocarbonyl)tetrahydro-1(2H)-pyridinecarboxylate
Synonyms	1-CBZ-4-CHLOROCARBONYLPIPERIDINE Piperidine-4-carbonyl chloride, N-CBZ protected 1-BENZYLOXYCARBONYLPIPERIDINE-3-CARBONYL CHLORIDE benzyl 4-(chlorocarbonyl)piperidine-1-carboxylate BENZYL 3-(CHLOROCARBONYL)PIPERIDINE-1-CARBOXYLATE benzyl 4-(carbonochloridoyl)piperidine-1-carboxylate 4-Chlorocarbonyl-piperidine-1-carboxylic acid benzyl ester BENZYL 3-(CHLOROCARBONYL)TETRAHYDRO-1(2H)-PYRIDINECARBOXYLATE Benzyl 4-(chlorocarbonyl)tetrahydro-1(2H)-pyridinecarboxylate 4-(2-bromoethyl)-2-piperidinecarboxylic acid (phenylmethyl) ester 1-Piperidinecarboxylic acid, 4-(chlorocarbonyl)-, phenylmethyl ester
CAS	10314-99-5
InChI	InChI=1/C14H16ClNO3/c15-13(17)12-7-4-8-16(9-12)14(18)19-10-11-5-2-1-3-6-11/h1-3,5-6,12H,4,7-10H2

BENZYL 3-(CHLOROCARBONYL)PIPERIDINE-1-CARBOXYLATE - Physico-chemical Properties

Molecular Formula	C14H16ClNO3
Molar Mass	281.73
Density	1.269±0.06 g/cm3(Predicted)
Boling Point	396.6±42.0 °C(Predicted)
Flash Point	193.6°C
Vapor Presure	1.69E-06mmHg at 25°C
pKa	-2.51±0.40(Predicted)
Storage Condition	2-8℃
Refractive Index	1.557

BENZYL 3-(CHLOROCARBONYL)PIPERIDINE-1-CARBOXYLATE - Risk and Safety

Hazard Symbols	C - Corrosive
Risk Codes	34 - Causes burns
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
UN IDs	3265
Hazard Note	Irritant

BENZYL 3-(CHLOROCARBONYL)PIPERIDINE-1-CARBOXYLATE - Introduction

4-chlorocarbonyltetrahydro-pyridine carboxylic acid benzyl ester, chemical formula C12H15ClNO3.

Properties: 4-chlorocarbonyltetrahydro-pyridinecarboxylic acid benzyl ester is a colorless or slightly yellow solid. It is stable at normal temperature and soluble in common organic solvents such as ethanol, dimethylformamide and dichloromethane.

Uses: 4-chlorocarbonyltetrahydro-pyridine carboxylic acid benzyl ester can be used as an intermediate in the synthesis of pharmaceuticals. It is often used in the synthesis of antidepressants, antiepileptic drugs, and beta-blockers. In addition, it can also be used in pesticide synthesis, dye synthesis and chemical research.

preparation method: 4-chlorocarbonyltetrahydro-pyridinecarboxylic acid benzyl ester can be prepared by the reaction of 4-chlorocarbonyltetrahydro-pyridine and benzyl alcohol. The specific preparation method may be to add sodium hydroxide to an organic solvent and heat to a suitable temperature, then add 4-chlorocarbonyltetrahydro-pyridine and benzyl alcohol, react for a period of time, and obtain the desired product by acidification.

Safety Information: 4-Chlorocarbonyltetrahydro-pyridinecarboxylic acid benzyl ester is relatively stable under normal conditions, but may decompose explosively under the action of high temperature, fire source or strong oxidant. When handling this compound, wear appropriate protective equipment to prevent contact with the skin and inhalation of its vapors. In case of contact or misuse, rinse immediately with water and seek medical help.

Last Update：2024-04-09 20:52:54